Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ CSF2 ▸ IL2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
AHSA1 ▸ VEGFA ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ IL3 ▸
TLR7 ▸ TLR8 ▸ RNF19A ▸ TLR6 ▸ IL15 ▸ LTA ▸ IL5 ▸
TLR10 ▸ TGFB1 ▸ IL33 ▸ TCF21 ▸ F2RL1 ▸ NOS2 ▸ IL18 ▸
TCF4 ▸ TCF25 ▸ TCF15 ▸ TCF7 ▸ TCF20 ▸ TCF24 ▸ TCF3 ▸
IL22 ▸ TCF12 ▸ CRK ▸ TCF23 ▸ TCF19 ▸ CSE ▸ PIK3CA ▸
PIK3R1 ▸ NFKBIA ▸ NA ▸ IL32 ▸ LPA ▸ MMP9 ▸ IL1RN ▸
PAF1 ▸ LEO1 ▸ APOB ▸ EGF ▸ IL31 ▸ CTR9 ▸ GRAP2 ▸
WDR61 ▸ CDC73 ▸ HGF ▸ S100A8 ▸ IL7 ▸ CXCR1 ▸ MMP2 ▸
IL11 ▸ IFNB1 ▸ ITGAM ▸ IL20 ▸ IL9 ▸ IL21 ▸ FGF2 ▸
IL16 ▸ IL25 ▸ IL19 ▸ IL26 ▸ POLDIP2 ▸ IL37 ▸ IL24 ▸
FAS ▸ IL27 ▸ SAA1 ▸ IL34 ▸ MMP3 ▸ INS ▸ EGFR ▸
NOS1 ▸ MIF ▸ AKT3 ▸ ALB ▸ PI3 ▸ AKT2 ▸ AKT1 ▸
CXCR2 ▸ CRP ▸ CASP3 ▸ MMP1 ▸ CASP4 ▸ IKBKB ▸ CD14 ▸
CALM3 ▸ NOX1 ▸ MMP13 ▸ CASP9 ▸ CASP8 ▸ CASP7 ▸ CD40LG ▸
NOS3 ▸ CASP1 ▸ CASP6 ▸ CASP16 ▸ CASP10 ▸ NOX4 ▸ CASP14 ▸
CASP2 ▸ F2R ▸ CASP5 ▸ CASP12 ▸ NOX3 ▸ PTX3 ▸ PLG ▸
NOX5 ▸ HMGB1 ▸ ITGB2 ▸ CHUK ▸ MYLIP ▸ PTK6 ▸ SELE ▸
MYD88 ▸ PTK2 ▸ IGF1 ▸ NOD1 ▸ LIF ▸ PTK7 ▸ TGFB2 ▸
TNFSF10 ▸ ERVK-6 ▸ CXCL12 ▸ IKBKG ▸ GP9 ▸ GP6 ▸ IFNA2 ▸
PRG2 ▸ MUC1 ▸ TREM1 ▸ SRC ▸ GP2 ▸ PRG4 ▸ PRG3 ▸
IL12B ▸ MMP8 ▸ GP5 ▸ LEP ▸ PTX4 ▸ STAT3 ▸ MAP3K7 ▸
PRKAR2A ▸ VCAM1 ▸ IFNA6 ▸ IL12A ▸ IFNA14 ▸ IFNA10 ▸ SOD3 ▸
PRKACB ▸ CRH ▸ WNK1 ▸ IFNA1 ▸ MPO ▸ IFNA16 ▸ MMP7 ▸
SERPINE1 ▸ IFNA13 ▸ IFNA21 ▸ IFNA8 ▸ SOD2 ▸ PRKACG ▸ IFNA4 ▸
PLD2 ▸ PRKAR1B ▸ HNRNPF ▸ SOD1 ▸ PRKAR2B ▸ PTBP2 ▸ IFNA7 ▸
HDAC2 ▸ IFNA5 ▸ S100A12 ▸ VIP ▸ MMP14 ▸ HNRNPH1 ▸ PTBP1 ▸
PAM ▸ CSF3 ▸ IFNA17 ▸ LTB ▸ PRKAR1A ▸ EGR1 ▸ CXCL10 ▸
HDAC1 ▸ SPP1 ▸ MMP27 ▸ MMP25 ▸ ELANE ▸ MMP28 ▸ MMP11 ▸
TNFRSF1A ▸ MMP20 ▸ MMP15 ▸ FGF1 ▸ IL1R1 ▸ MSH3 ▸ CAT ▸
NOD2 ▸ EDN1 ▸ MMP19 ▸ MMP21 ▸ CSK ▸ SETD2 ▸ CCL3 ▸
PLD1 ▸ MMP26 ▸ MMP10 ▸ MMP12 ▸ MMP17 ▸ MMP16 ▸ MMP24 ▸
TGFB3 ▸ TRAF6 ▸ PLD3 ▸ MSH5 ▸ FGF7 ▸ PLA2G1B ▸ PLD6 ▸
PLD4 ▸ FASLG ▸ SYT1 ▸ PLD5 ▸ MSH4 ▸ ANGPT2 ▸ QRICH1 ▸
SST ▸ MSH2 ▸ CD4 ▸ TAB1 ▸ MSH6 ▸ CD8A ▸ NAALADL1 ▸
QRICH2 ▸ AHR ▸ MAP2K1 ▸ FGF23 ▸ ADIPOQ ▸ FGF19 ▸ FGF6 ▸
CSF1 ▸ FGF16 ▸ RAC1 ▸ C1QB ▸ FGF3 ▸ FGF4 ▸ FGF8 ▸
FGF20 ▸ SELP ▸ HDAC5 ▸ FGF11 ▸ FGF9 ▸ CSRP1 ▸ ITGB1 ▸
C1QA ▸ PPARG ▸ SOCS3 ▸ P2RY6 ▸ FGF17 ▸ STAT1 ▸ FGF5 ▸
FGF18 ▸ CXCL1 ▸ HMOX1 ▸ FGF14 ▸ TXN ▸ CD46 ▸ CD28 ▸
ETS1 ▸ SELL ▸ CD38 ▸ PDLIM7 ▸ FGF12 ▸ TNFSF12 ▸ SAA2 ▸
LTF ▸ FGF21 ▸ STX2 ▸ FGF10 ▸ NGF ▸ HDAC6 ▸ FGF22 ▸
FGF13 ▸ HDAC3 ▸ HSPD1 ▸ HSPB1 ▸ HDAC8 ▸ ECM2 ▸ RHO ▸
HES1 ▸ STX1A ▸ TNFSF13B ▸ MTX1 ▸ MTOR ▸ MUC12 ▸ TRPV1 ▸
HDAC11 ▸ TNMD ▸ MUC22 ▸ HDAC7 ▸ MUC20 ▸ PPARA ▸ NPS ▸
RHOA ▸ ANGPT1 ▸ HDAC9 ▸ GPI ▸ APC ▸ PDGFB ▸ PF4 ▸
BCL3 ▸ AGTR2 ▸ CXCR3 ▸ STAT4 ▸ MUC7 ▸ TAT ▸ MUC16 ▸
CR1 ▸ CD79A ▸ MUC15 ▸ ECM1 ▸ PDCD11 ▸ CD8B ▸ RBBP4 ▸
RBBP7 ▸ PLA2G4A ▸ PLAU ▸ ST8SIA2 ▸ IL2RA ▸ MUC4 ▸ NAP1L4 ▸
CFTR ▸ CISH ▸ MUC17 ▸ ANG ▸ MUC21 ▸ HSPG2 ▸ ITIH4 ▸
MUC8 ▸ CXCR4 ▸ HDAC4 ▸ PRTN3 ▸ MUC6 ▸ PRKCD ▸ SETBP1 ▸
HDAC10 ▸ SAA4 ▸ MUC19 ▸ MUC13 ▸ CPOX ▸ MUC2 ▸ NR4A2 ▸
ESR1 ▸ PKD1 ▸ UTP15 ▸ DEFA1 ▸ MT4 ▸ ARG2 ▸ HES5 ▸
PRR18 ▸ PRR7 ▸ SEA ▸ IFI44 ▸ PRR19 ▸ IBD3 ▸ ADAM17 ▸
PRKCA ▸ BCL2 ▸ ADCYAP1 ▸ UTP6 ▸ CXCL9 ▸ GRP ▸ NUP43 ▸
ARG1 ▸ HBEGF ▸ UTP20 ▸ PRR25 ▸ CXCL17 ▸ PGF ▸ IBD7 ▸
TAC4 ▸ CALM2 ▸ ELF4 ▸ HES7 ▸ IRAK1 ▸ ICOSLG ▸ MAP2K7 ▸
MAP3K1 ▸ APEX1 ▸ CYP1A1 ▸ FGG ▸ DDIT3 ▸ ICAM3 ▸ HES3 ▸
IBD4 ▸ DUSP1 ▸ PRKAA2 ▸ HES4 ▸ PTAFR ▸ ETS2 ▸ CCL20 ▸
IBD9 ▸ SELPLG ▸ CCR5 ▸ PRR15 ▸ JAK2 ▸ FGA ▸ HDC ▸
MUC5AC ▸ FOXO3 ▸ IL17F ▸ IRAK3 ▸ HES2 ▸ TF ▸ ICAM2 ▸
FCGR1A ▸ LPL ▸ PGD ▸ CTNNB1 ▸ ADAM11 ▸ PRR21 ▸ PRKAB1 ▸
RELB ▸ PRR16 ▸ PRKAG1 ▸ MET ▸ UTP18 ▸ CHI3L1 ▸ SIGLEC7 ▸
NTS ▸ TAC3 ▸ CXCL6 ▸ IBD8 ▸ PRR26 ▸ TAC1 ▸ PRR12 ▸
IBD2 ▸ ROCK2 ▸ PAEP ▸ BCL10 ▸ ICAM5 ▸ AZU1 ▸ A2M ▸
EPO ▸ UTP23 ▸ ELF3 ▸ RNASE3 ▸ MPL ▸ HES6 ▸ MT3 ▸
PRDX2 ▸ EMD ▸ TGFA ▸ PRR3 ▸ PRR9 ▸ PRR14 ▸ CALM1 ▸
NR0B1 ▸ RENBP ▸ PRKAB2 ▸ PRR11 ▸ TP53 ▸ CXCL11 ▸ PRR22 ▸
PRKAA1 ▸ PRR13 ▸ SMAD3 ▸ PRR4 ▸ BRAF ▸ IBD5 ▸ PRKAG2 ▸
IBD6 ▸ IL1R2 ▸ PRL ▸ UTP3 ▸ PRR24 ▸ PRR5 ▸ TFPI ▸
OSM ▸ ICAM4 ▸ TPO ▸ PAK2 ▸ TEC ▸ CD86 ▸ GAST ▸
HCG15 ▸ CPB2 ▸ HCG17 ▸ ALX4 ▸ REL ▸ FUT7 ▸ RAC2 ▸
S100A9 ▸ SERPINB2 ▸ ELF1 ▸ ARSA ▸ DNASE2 ▸ FUT8 ▸ MYO10 ▸
SMAD5 ▸ CP ▸ IL23A ▸ GRB14 ▸ WNT11 ▸ TRAF2 ▸ STAT5A ▸
F7 ▸ APOA2 ▸ C3 ▸ HMGB4 ▸ SMAD2 ▸ DPM1 ▸ ELF5 ▸
ASIP ▸ BCL6 ▸ CYP19A1 ▸ FMR1 ▸ HCG27 ▸ TNFSF11 ▸ FUT4 ▸
HCG24 ▸ MRXS5 ▸ HRH1 ▸ CAPN8 ▸ HCG11 ▸ HMGB3 ▸ ABL1 ▸
JAK3 ▸ MPG ▸ PDGFA ▸ PROK1 ▸ CDC42 ▸ CGN ▸ RAC3 ▸
TACR1 ▸ CTSS ▸ GHRH ▸ CAPN5 ▸ CTGF ▸ VAV1 ▸ ELAVL1 ▸
DEFA1B ▸ FUT9 ▸ CEACAM6 ▸ ALX3 ▸ FXYD1 ▸ SYK ▸ FOXO1 ▸
PARK2 ▸ APOA1 ▸ AGTR1 ▸ C1orf228 ▸ RAG1 ▸ GH1 ▸ VCP ▸
DNASE1 ▸ GRB2 ▸ NLRP3 ▸ PAK1 ▸ CAPN7 ▸ TNP1 ▸ GRB10 ▸
WNT6 ▸ TMSB4X ▸ GRPR ▸ CAPN1 ▸ CAPN13 ▸ IGF2 ▸ SPP2 ▸
RABEPK ▸ MKNK1 ▸ PTGS1 ▸ THBD ▸ PTPN11 ▸ HCG9 ▸ MBP ▸
CAPN9 ▸ CAPN12 ▸ CAPN11 ▸ WNT4 ▸ CD83 ▸ DUOX1 ▸ SMAD1 ▸
HCG21 ▸ CA1 ▸ FUT1 ▸ PARK7 ▸ CD2 ▸ SOAT1 ▸ TBP ▸
FGB ▸ PAK4 ▸ CNR1 ▸ CD163 ▸ DPM2 ▸ F2RL2 ▸ CSTA ▸
BCR ▸ HCG4 ▸ PAH ▸ CXCL14 ▸ JAK1 ▸ SMAD9 ▸ MEPE ▸
SFXN1 ▸ CD69 ▸ CNR2 ▸ NPY4R ▸ KDR ▸ KRT10 ▸ IRS1 ▸
HRAS ▸ CDH5 ▸ TNFRSF9 ▸ CXCL2 ▸ IDO1 ▸ MAP2K3 ▸ DPM3 ▸
CAPN14 ▸ SMAD4 ▸ FUT2 ▸ ALX1 ▸ LBP ▸ FOXO6 ▸ MAP2K4 ▸
CD44 ▸ HCG14 ▸ UCN2 ▸ MYO16 ▸ WNT2 ▸ FUT5 ▸ SCARB1 ▸
HMGB2 ▸ VDR ▸ AR ▸ APOE ▸ HCG25 ▸ DDX58 ▸ FOSL1 ▸
WNT1 ▸ ATP8A2 ▸ WNT16 ▸ MAP2K2 ▸ CPB1 ▸ NPY ▸ PTHLH ▸
TSC22D3 ▸ AREG ▸ ITGA5 ▸ MAP2K6 ▸ ACKR3 ▸ PTPN22 ▸ CD1D ▸
FUT10 ▸ RNASE2 ▸ PITX1 ▸ CAPN2 ▸ CSH2 ▸ IFIH1 ▸ FCER2 ▸
PINK1 ▸ SLPI ▸ HCG8 ▸ F10 ▸ TRNAI1 ▸ SMAD7 ▸ CEBPB ▸
FUT11 ▸ FOXP3 ▸ MYO6 ▸ ADAM19 ▸ TNPO1 ▸ PDCD4 ▸ GSTM1 ▸
SPESP1 ▸ CX3CL1 ▸ TNP2 ▸ HCG18 ▸ ELF2 ▸ BMP2 ▸ FUT6 ▸
ADM ▸ SERPINE2 ▸ MTA3 ▸ VASP ▸ WNT3 ▸ CCL5 ▸ CAPN6 ▸
GIP ▸ CXCL16 ▸ MTA2 ▸ ROCK1 ▸ CXCL5 ▸ MAP2K5 ▸ PAK7 ▸
CEBPA ▸ ALOX5 ▸ CEACAM1 ▸ HCG16 ▸ FOXO4 ▸ CXCR6 ▸ CSH1 ▸
CXCL13 ▸ HCG26 ▸ HIF1A ▸ CDH1 ▸ PAK3 ▸ CAPN10 ▸ HLA-DRB1 ▸
TPT1 ▸ MTA1 ▸ CXCL3 ▸ FCGR2B ▸ ADAM10 ▸ NPY6R ▸ MYO19 ▸
HBD ▸ BPI ▸ FUT3 ▸ RETN ▸ HCG22 ▸ POU2F1 ▸ GAL ▸
PAK6 ▸ KLRB1 ▸ MEFV ▸ CCL4 ▸ NR4A1 ▸ TNFRSF1B ▸ MAPKAPK2 ▸
GRB7 ▸ SMAD6 ▸ HCG20 ▸ NFKBIZ ▸ HCG23 ▸ CAPN15 ▸ CYP1A2 ▸
FGFR2 ▸ OXA1L ▸ NAMPT ▸ BLM ▸ ANPEP ▸ KLK3 ▸ CAPN3 ▸
KSR2 ▸ CTSB ▸ PGP ▸ ADORA3 ▸ LPAR5 ▸ CCR8 ▸ GNB1 ▸
C5AR1 ▸ GALR1 ▸ S1PR2 ▸ TAS2R14 ▸ NPY5R ▸ HTR1A ▸ HRH3 ▸
CCR7 ▸ TAS2R39 ▸ S1PR4 ▸ GABBR1 ▸ TAS2R8 ▸ OPRK1 ▸ GRM2 ▸
DRD3 ▸ GNAI3 ▸ ADORA1 ▸ TAS2R20 ▸ NPB ▸ S1PR1 ▸ APLNR ▸
OXGR1 ▸ HRH4 ▸ HEBP1 ▸ PDYN ▸ GRM6 ▸ BDKRB1 ▸ P2RY12 ▸
KNG1 ▸ RXFP3 ▸ P2RY13 ▸ HCAR3 ▸ GNAT3 ▸ DARC ▸ ADRA2C ▸
CCL25 ▸ SSTR1 ▸ NMUR2 ▸ CHRM2 ▸ BDKRB2 ▸ GNG2 ▸ CCR9 ▸
HCAR2 ▸ ADRA2A ▸ CHRM4 ▸ CCR6 ▸ NPY1R ▸ CCL27 ▸ OPRL1 ▸
NPBWR1 ▸ C3AR1 ▸ TAS2R19 ▸ GALR3 ▸ GRM3 ▸ TAS2R31 ▸ TAS2R16 ▸
CX3CR1 ▸ S1PR3 ▸ CCL16 ▸ PPY ▸ CCR2 ▸ GNAI1 ▸ TAS2R10 ▸
TAS2R3 ▸ P2RY4 ▸ INSL5 ▸ TAS2R46 ▸ MTNR1B ▸ HTR1D ▸ TAS2R9 ▸
CCL28 ▸ HCAR1 ▸ NPY2R ▸ XCR1 ▸ GNAI2 ▸ TAS2R13 ▸ TAS2R7 ▸
TAS2R41 ▸ TAS2R40 ▸ NMU ▸ CCR10 ▸ GRM7 ▸ DRD2 ▸ MT-RNR2 ▸
SSTR3 ▸ PMCH ▸ MCHR1 ▸ SSTR5 ▸ DRD4 ▸ PENK ▸ TAS2R45 ▸
MCHR2 ▸ MTNR1A ▸ PPBP ▸ TAS2R1 ▸ U2AF1 ▸ NPBWR2 ▸ NMUR1 ▸
HTR1B ▸ TAS2R30 ▸ PTGDR2 ▸ TAS2R50 ▸ GRM4 ▸ GRM8 ▸ CCR4 ▸
CCR1 ▸ CCL19 ▸ TAS2R38 ▸ TAS2R5 ▸ PTGER3 ▸ PNOC ▸ HTR5A ▸
GABBR2 ▸ SSTR4 ▸ ANXA1 ▸ FPR3 ▸ FPR1 ▸ GALR2 ▸ OPRD1 ▸
TAS2R60 ▸ OXER1 ▸ TAS2R4 ▸ HTR1F ▸ TAS2R43 ▸ S1PR5 ▸ RXFP4 ▸
SUCNR1 ▸ HTR1E ▸ SSTR2 ▸ GPER1 ▸ ADRA2B ▸ TAS2R42 ▸ PYY ▸
Data information
Please see the Gene Interactions Track Manual.