Gene interactions and pathways from curated databases and text-mining

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EMP1 — GRAP2

Text-mined interactions from Literome

Curtis et al., Journal of thrombosis and haemostasis : JTH 2009 : On the basis of the importance of p38 mitogen activated protein kinase ( MAPK ) in endothelial responses to inflammatory stimuli, we sought to define the role of p38 in EMP generation and function
Ryu et al., Blood Purif 2011 (MAP Kinase Signaling System) : ( 1 ) Indoxyl sulfate induced EMP release in HUVECs in a dose dependent fashion ; ( 2 ) all drugs ( 10-50 µM ) inhibited EMP generation induced by indoxyl sulfate, with clopidogrel being the most effective ; ( 3 ) the p38 MAPK inhibitor suppressed EMP generation induced by indoxyl sulfate, and ( 4 ) clopidogrel significantly suppressed MAPK signaling activated by indoxyl sulfate, with the most potency on p38