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TAB1 — TGFB3
Text-mined interactions from Literome
Zhang et al., Nat Med 2000
(Cardiac Output, Low...) :
The
transforming-growth-factor-beta activated kinase
TAK1 is a member of the mitogen activated protein kinase kinase kinase family, which couples extracellular stimuli to gene transcription
Kawahara et al., J Med Invest 2001
(Atrophy...) :
These cells expressed the Toll-like receptor 4 (TLR4) mRNA and its protein, and type I Hp LPS phosphorylated
transforming growth factor beta activated kinase 1 ( TAK1 ) and
TAK1 binding protein 1 (TAB1) in association with up-regulation of the TLR4 expressions, suggesting that type I Hp LPS evoked distinct TLR4 signaling
Kusumoto et al., Am J Physiol Gastrointest Liver Physiol 2005
:
Ecabet completely blocked the LPS triggered phosphorylation of
transforming growth factor-beta activated kinase 1 ( TAK1 ) and
TAK1 binding protein 1 , activation of caspase 8, loss of mitochondrial membrane potential, release of cytochrome c, activation of caspase 3, and appearance of apoptotic cells
Neil et al., Cancer Res 2008
(Disease Progression) :
Altered
TAB1 : I kappaB kinase interaction
promotes transforming growth factor beta mediated nuclear factor-kappaB activation during breast cancer progression
Sethi et al., Mol Cancer Ther 2008
(Neoplasm Invasiveness...) :
Pinitol also suppressed the NF-kappaB reporter activity induced by tumor necrosis factor receptor (TNFR)-1, TNFR associated death domain, TNFR associated factor-2,
transforming growth factor-beta activated kinase-1 ( TAK-1 )
/TAK1 binding protein-1 , and IkappaBalpha kinase but not that induced by p65