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CDC6 — CDH1

Text-mined interactions from Literome

Petersen et al., Genes Dev 2000 : Furthermore, APC, in association with CDH1, ubiquitinates CDC6 in vitro, and both APC and CDH1 are required and limiting for CDC6 proteolysis in vivo
Wäsch et al., Nature 2002 : Furthermore, Clb5 degradation was thought to be necessary for effective dephosphorylation and activation of the APC regulatory subunit Cdh1 ( also known as Hct1 ) and the cyclin dependent kinase inhibitor Sic1 by the phosphatase Cdc14 , allowing mitotic kinase inactivation and mitotic exit
Sideridou et al., J Cell Biol 2011 : Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins ... Prompted by these findings, we discovered that Cdc6 repressed CDH1 transcription by binding to the E-boxes of its promoter, leading to dissociation of the chromosomal insulator CTCF, displacement of the histone variant H2A.Z, and promoter heterochromatinization