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BCL2 — CTNNB1

Text-mined interactions from Literome

Xie et al., Crit Rev Immunol 2006 : Transcriptional coactivator beta-catenin recruited by TCF-1, and steroid receptor coactivators ( SRCs ) recruited by ROR gamma t, are also required for optimal stimulation of Bcl-xL expression
Li et al., Oncogene 2007 (Colonic Neoplasms) : To examine the possible direct transcriptional regulation of rat Bcl-2 by beta-catenin/Tcf , we cloned and characterized the corresponding promoter region and found 70.1 % similarity with its human counterpart, BCL2 ... Bcl-2 promoter activity was increased in response to LiCl and exogenous beta-catenin , including oncogenic mutants of beta-catenin found in PhIP induced colon tumors ... As expected, beta-catenin induced its downstream target c-Myc, as well as E2F1 and Bcl-2 , and this was blocked by siRNA to c-Myc or E2F1
Li et al., Mol Carcinog 2007 : Our data suggest that Bcl-2 expression is induced by beta-catenin and modulated by Pg ... We show that the inhibition of beta-catenin dependent TCF transactivation had no effect on Bcl-2 levels, suggesting that induction of Bcl-2 expression by beta-catenin and its modulation by Pg may involve factors other than, or in addition, to, TCF
Lapham et al., Gene 2009 (Colorectal Neoplasms) : The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells ... The activity of the Bcl-w promoter was increased or decreased, respectively, by overexpression of beta-catenin or dominant negative TCF4
Schenkel et al., J Immunol 2010 : Further, beta-catenin expression induced the antiapoptotic factor BcL-xL , suggesting that beta-catenin may mediate protection against activation induced cell death
Xia et al., Hepatobiliary Pancreat Dis Int 2012 (Disease Models, Animal...) : Upregulation of GSK-3beta/beta-catenin signaling increased Bcl-2 , survivin and cyclin D1