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CTNNB1 — FZD7

Text-mined interactions from Literome

Merle et al., Gastroenterology 2004 (Carcinoma, Hepatocellular...) : These observations suggest that the Wnt/beta-catenin signal transduction pathway is involved much more commonly in the molecular pathogenesis of HCC than previously recognized because FZD7 overexpression occurred early in the disease process, stabilized wild-type beta-catenin levels, and contributed to enhanced tumor cell migration
Vincan et al., Dev Dyn 2010 (Colorectal Neoplasms) : We demonstrate that the FZD7 promoter is regulated by beta-catenin in colorectal cancer cells and observed decreased promoter activity in cells grown on fibronectin but not collagen I or collagen IV
Tanaka et al., Proc Natl Acad Sci U S A 1998 (Esophageal Neoplasms) : Finally, coexpression of FzE3 with Lef-1 transcription factor enhanced beta-catenin translocation to the nucleus ... These observations suggest that FzE3 gene expression may down-regulate APC function and enhance beta-catenin mediated signals in poorly differentiated human esophageal carcinomas