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INS — PIK3CG

Pathways - manually collected, often from reviews:

• KEGG mTOR signaling pathway: IGF1/INS → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, indirect effect)
  

Text-mined interactions from Literome

Li et al., Endocrinology 2006 : These findings indicate that PI3-Kgamma deficiency impairs insulin secretion, resulting in compensatory islet growth to maintain normoglycemia
Pigeau et al., Diabetes 2009 (Insulinoma...) : Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells ... We therefore investigated the role of the G-protein coupled PI3Kgamma and its catalytic subunit p110gamma in the regulation of insulin granule recruitment and exocytosis