Gene interactions and pathways from curated databases and text-mining

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MAPK10 — PDGFA

Text-mined interactions from Literome

Hanada et al., Biol Pharm Bull 1999 : PDGF-AB stimulated mitogen activated protein ( MAP ) kinases , and PDGF induced MAP kinase activation was inhibited by genistein
Ricono et al., American journal of physiology. Renal physiology 2002 (MAP Kinase Signaling System) : PDGF AA and PDGF BB significantly increased the activities of phosphatidylinositol 3-kinase (PI 3-K) and mitogen activated protein kinase ( MAPK ) ... Although PDGF AA stimulates PI 3-K and MAPK activity, it is not mitogenic and only modestly chemotactic
Liu et al., Surgery 2002 : In contrast, C3 did not significantly affect DNA synthesis in response to PDGF-AB or activation of mitogen activated protein kinase , a signaling mediator of PDGF stimulated proliferation
Oak et al., Arterioscler Thromb Vasc Biol 2003 (MAP Kinase Signaling System) : Short-term and long-term treatment of VSMCs with RWPCs markedly reduced PDGFAB induced production of reactive oxygen species and phosphorylation of p38 MAPK
Lubinus et al., J Biol Chem 1994 : We investigated the effects of platelet derived growth factor (PDGF) AA and PDGF BB on activation of MAPK in human dermal fibroblasts, and asked whether its activation correlates with proliferative responses of human fibroblasts to PDGF AA and PDGF BB ... Thus both PDGF AA and PDGF BB are potent activators of MAPK in human dermal fibroblasts
Karenberg et al., Exp Cell Res 1994 : Whereas PDGF-BB effectively stimulated all three events, PDGF-AA failed to stimulate the phosphatidylinositol-3 kinase activity, but stimulated the mitogen activated protein kinase to a maximum extent