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DUSP1 — NOS2

Text-mined interactions from Literome

Begum et al., Am J Physiol Cell Physiol 2000 (Insulin Resistance...) : High glucose and insulin inhibit VSMC MKP-1 expression by blocking iNOS via p38 MAPK activation
Nelin et al., Am J Physiol Cell Physiol 2007 (Inflammation) : We found that overexpression of MKP-1 resulted in lower iNOS expression and NO production but greater urea production in response to LPS
Wang et al., J Biol Chem 2009 : To understand the molecular basis for the increase in NO production, we studied the role of MKP-1 in the regulation of iNOS expression ... Our results suggest that MKP-1 may negatively regulate iNOS expression by controlling the expression of miR-155 and consequently the STAT pathway via SOCS-1
Turpeinen et al., Mediators Inflamm 2011 : The role of dual specificity phosphatase 1 (DUSP1) in inducible nitric oxide synthase (iNOS) expression in A549 human pulmonary epithelial cells, J774 mouse macrophages and primary mouse bone marrow derived macrophages ( BMMs ) was investigated ... Down-regulation of DUSP1 by siRNA increased p38 MAPK phosphorylation and iNOS expression in A549 and J774 cells