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NFKB1 — TAB2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: TAB2 — NFKB1 (physical association, affinity chromatography technology) Baek et al., Cell 2002*
• IRef Biogrid Interaction: TAB2 — NFKB1 (direct interaction, pull down) Baek et al., Cell 2002*
• IRef Innatedb Interaction: NFKB1 — TAB2 (unknown, -) Baek et al., Cell 2002*

Text-mined interactions from Literome

Takaesu et al., Mol Cell 2000 : Expression of TAB2 induces JNK and NF-kappaB activation, whereas a dominant negative mutant TAB2 impairs their activation by IL-1
Mizukami et al., Mol Cell Biol 2002 (MAP Kinase Signaling System) : Dominant negative forms of TAK1 and TAB2 inhibit NF-kappaB activation induced by overexpression of RANK ... Furthermore, in murine monocyte RAW 264.7 cells, dominant negative forms of TAK1 and TAB2 inhibit NF-kappaB activation induced by RANKL and endogenous TAK1 is activated in response to RANKL stimulation
Ishitani et al., EMBO J 2003 (Inflammation) : TAB2 , a TAK1 binding protein, is involved in IL-1 induced NF-kappaB activation by physically linking TAK1 to TRAF6
Mashima et al., J Biol Chem 2005 : Furthermore, we demonstrated that NF-kappaB activation induced by TRAF6 and TAB2 was impaired by co-expression of FLN29, suggesting FLN29 may regulate the downstream of TRAF6
Morlon et al., Hum Mol Genet 2005 (Ectodermal Dysplasia) : TAB2 , TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd ... Moreover, we show that dominant negative forms of TAB2 , TRAF6 and TAK1 blocked the NF-kappaB activation induced by Edaradd
Zhuang et al., Cell Signal 2006 : Drosophila TAB2 is required for the immune activation of JNK and NF-kappaB
Tian et al., J Biol Chem 2007 : RBCK1 negatively regulates tumor necrosis factor- and interleukin-1 triggered NF-kappaB activation by targeting TAB2/3 for degradation
Suzuki et al., J Biol Chem 2007 (Cell Transformation, Viral...) : Constitutive activation of TAK1 by HTLV-1 tax dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-kappaB
Yu et al., Biochem Biophys Res Commun 2008 : We found that TAB2 physically interacts with Tax and augments Tax induced NF-kappaB activity
Tareen et al., Virology 2011 : We show that human Trim5a also affects levels of TAB2, resulting in abrogation of TAB2 dependent NF-kappaB activation