Gene interactions and pathways from curated databases and text-mining

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CD27 — IL10

Text-mined interactions from Literome

Jung et al., Eur J Immunol 2000 : Regulation of CD27 expression in the course of germinal center B cell differentiation : the pivotal role of IL-10
Avery et al., J Immunol 2005 : We found that CD27 is also up-regulated on memory B cells in an IL-10 dependent and division dependent manner, and that ISC segregated into the CD27 ( high ) subset of activated memory B cells irrespective of the acquired expression of CD38
Arimoto-Miyamoto et al., Immunology 2010 : In contrast, the CD70-CD27 interaction diminished the production of an immunoregulatory cytokine IL-10
Hartwig et al., J Immunol 1997 : In addition, testing a spectrum of different cytokines indicated that IL-4 and TGF, but not IL-2, IL-10 , or IFN-gamma, prevented up-regulation of CD27L expression on activated B cells even when activation was induced by Ig signaling
Nagumo et al., Immunology 1998 : On the other hand, IL-10 diminished CD27 expression in B cells