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CA2 — CD44

Text-mined interactions from Literome

Singleton et al., Cell Motil Cytoskeleton 2002 (Calcium Signaling) : CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate ( IP3 ) receptor mediated Ca2+ signaling during hyaluronan ( HA ) -induced endothelial cell migration
Bourguignon et al., J Biol Chem 2006 (Carcinoma, Squamous Cell...) : Taken together, our findings suggest that CD44 interaction with LARG and EGFR plays a pivotal role in Rho/Ras co-activation, PLC epsilon-Ca2+ signaling, and Raf/ERK up-regulation required for CaMKII mediated cytoskeleton function and in head and neck squamous cell carcinoma progression
David et al., Cell Prolif 2008 (Neoplasm Invasiveness) : HA-provoked cellular invasiveness resulted from CD44 mediated increase in cytosolic [Ca2+ ] and its subsequent hydrolysis due to ADAM ( a disintegrin and metalloprotease ) proteolytic activity
Nunomura et al., J Biol Chem 1997 : Regulation of CD44-protein 4.1 interaction by Ca2+ and calmodulin