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FOS — IGF1
Text-mined interactions from Literome
Xu et al., J Neuropathol Exp Neurol 2001
(Diabetes Mellitus, Type 1...) :
The delayed
IGF-1 expression may
affect C-FOS induction and may be responsible for the delay in the NGF response in diabetic rats
Kim et al., Biochem Biophys Res Commun 2004
(MAP Kinase Signaling System) :
Furthermore,
IGF-II remarkably
increased the DNA binding activities of NF-kappaB and
AP-1 , and the IL-8 promoter activity
Freiss et al., J Steroid Biochem Mol Biol 2005
(Breast Neoplasms) :
We have tested the effects of two Eli-Lilly compounds, LY 117, 018 and raloxifene, on E2-regulated and
IGF-I induced proliferation or
AP-1 activity in human breast cancer cells ... Moreover, raloxifene was the most efficient molecule to prevent
IGF-I induced
AP-1 activity, with a significant effect observed with a concentration as low as 5 x 10 ( -11 ) M in the presence of IGF-I alone
Jia et al., J Cell Mol Med 2011
:
These data demonstrate a cross-talk between IGF-1R and AT-1R in AT-II and
IGF-1 induced Cx43 expression in SV SMCs involving Erk 1/2 and downstream
activation of the
AP-1 transcription factor
Yang et al., Biochem J 2011
(Colonic Neoplasms) :
IGF-1 induced MAT2A promoter activity and
increased nuclear protein binding to USF ( upstream stimulatory factor ) /c-Myb, YY1 ( Yin and Yang 1 ), E2F,
AP-1 ( activator protein 1 ) and NF-?B ( nuclear factor ?B ) consensus elements
Puzik et al., Cytokine 2012
(Infection) :
Furthermore the
effect of
IGF-I on cytokine expression, apoptosis and the DNA binding activity of
AP-1 and NF?B was evaluated
Torres-Aleman et al., Neuroscience 1998
:
In addition,
insulin-like growth factor-I increased intracellular Ca2+ levels in Purkinje cells and
c-Fos in dividing glioblasts