Gene interactions and pathways from curated databases and text-mining

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ESR1 — SERPINB9

Text-mined interactions from Literome

Jiang et al., Oncogene 2007 : Expressing elevated levels of estrogen receptor alpha (ERalpha) increases the induced level of PI-9 , and makes tamoxifen ( TAM ), but not raloxifene or ICI 182,780, a potent inducer of PI-9
Jiang et al., Endocrinology 2008 (Breast Neoplasms) : Because 4-hydroxytamoxifen, raloxifene, and ICI 182,780/Faslodex all block genistein induction of PI-9 and elevated levels of ERalpha enhance induction of PI-9, genistein acts via ERalpha to induce PI-9 ... Increasing levels of ERalpha in breast cancer cells results in a progressive increase in induction of PI-9 by genistein and in the cell 's ability to evade killing by NK cells