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IL2 — IL7

Text-mined interactions from Literome

Liu et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 1997 (Yang Deficiency) : Hemorheological indexes, brain noradrenaline ( NE ), adrenocorticotropine ( ACTH ), beta endorphin, cortisol, estradiol, testosterone, interleukin-II (IL-2), tumour necrosis factor (TNF) in the blood, and rat spleen 's lymphocyte transformation and induction of IL-2 and the activity of natural killer cells ( NKC )
Song et al., Neuroscience 1999 : As well, interleukin-6 and interleukin-2 were both found to reduce the homovanillic acid response associated with the stress, and interleukin-2 promoted a decline of homovanillic acid levels
Greene et al., Biochim Biophys Acta 1999 : Interleukin-1 receptor associated kinase and TRAF-6 mediate the transcriptional regulation of interleukin-2 by interleukin-1 via NFkappaB but unlike interleukin-1 are unable to stabilise interleukin-2 mRNA
Matsuura et al., Dig Liver Dis 2000 (Crohn Disease) : The effect of interleukin-4 on lamina propria mononuclear cells from Crohn 's disease, ulcerative colitis and control mucosa was assessed on various T-cell functions : interleukin-2 induced cytotoxicity, soluble interleukin-2 receptor and interleukin-2 production, and expression of mRNA for interleukin-2R and interferon-gamma
Kelley et al., Lipids 2001 : CLA supplementation did not alter the in vitro secretion of prostaglandin E2, leukotriene B4, interleukin-1beta (IL-1beta), or tumor necrosis factor alpha (TNFalpha) by PBMC simulated with lipopolysaccharide, and the secretion of IL-2 by PBMC stimulated with phytohemagglutinin
Xue et al., Proc Natl Acad Sci U S A 2002 : IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes
Brenchley et al., Clin Exp Immunol 2002 : Memory T-cells will divide in response to exogenous IL-7 but only in the presence of naïve T-cells and IL-2
Dalhoff et al., Lancet Infect Dis 2003 : In general, most fluoroquinolone derivatives superinduce in-vitro interleukin 2 synthesis but inhibit synthesis of interleukin 1 and tumour necrosis factor (TNF)alpha ; furthermore, they enhance significantly the synthesis of colony stimulating factors (CSF)
Walker et al., J Immunol 1992 (Mycobacterium Infections) : In particular, IL-1 (-alpha and -beta), IL-2 , TNF (-alpha and -beta), and IFN-gamma mRNA were readily detected , whereas IL-3, IL-4, IL-5, IL-6, IL-7 , and granulocyte-macrophage colony stimulating factor mRNA were not detected, or were detectable only at very low levels
Liu et al., J Immunother 2006 : IL-7 alone did not induce significant proliferation of any tumor-reactive T-cell population, whereas IL-2 and IL-15 induced significant proliferation of tumor-reactive T lymphocytes from both sources
Naume et al., J Immunol 1991 : Both IL-7 and IL-2 induced comparable levels of 75-kDa TNFR expression, whereas IL-2R alpha expression was higher in IL-7 stimulated CD56+ cells
Fernández et al., Appl Environ Microbiol 2007 : Furthermore, expression of a mature mouse IL-2 gene resulted in interleukin secretion without the requirement for a leader sequence
Van Vlasselaer et al., Cell Immunol 1991 : Whereas thymocytes show a minimal response to phytohemagglutinin ( PHA ), IL-2, or IL-4 alone, they proliferate vigorously when cocultured with irradiated cloned NS cells in the presence of PHA or IL-2 or IL-4, but not with IL-1, IL-3, IL-6, IL-7 , IFN-gamma, or GM-CSF
Tomizawa et al., Clin Exp Immunol 1991 : Of the cytokines studied, interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) were involved in the regulation of IL-2R on B cells
Scholz et al., Cell Signal 1989 (Leukemia) : Synergistic induction of interleukin 2 receptor ( TAC ) expression on YT cells by interleukin 1 or tumor necrosis factor alpha in combination with cAMP inducing agents
Conlon et al., Blood 1989 : Thus, IL-7 may cause proliferation of thymocytes directly, not indirectly, through production of IL-2 , IL-4, or IL-6
Schultzberg et al., Neuroscience 1989 : These antisera also inhibited stimulation of interleukin-2 receptor expression by purified human interleukin-1
Falk et al., Lymphokine Res 1989 : The cytokine interleukin-1 plays an important role in the induction of IL-2 secretion and IL-2 receptor expression
Lee et al., J Rheumatol 1985 (Arthritis...) : The low IL-2 levels was not a result of degradation or consumption of endogenously produced interleukin
Anastassakos et al., Clin Exp Immunol 1987 (Chronic Disease...) : To test the hypothesis that reduced lymphocyte transformation in response to PHA in chronic hepatitis B virus infection might be due to deficient lymphokine production, lymphocyte transformation was measured in the presence or absence of exogenous interleukin 1, interleukin 2 or both, or, as a source of mixed lymphokines, supernatants from mixed lymphocyte reactions
Uchiyama et al., Microbiol Immunol 1986 : T cells obtained by the nylon wool column method alone produced IL 2 on TSST-1 stimulation in the presence of either macrophages or a macrophage lysate containing interleukin 1
Mukaida et al., J Immunol 1987 (Leukemia) : Signal requirement for interleukin-1 dependent interleukin 2 production by a human leukemia derived HSB.2 subclone
Soulillou et al., Eur J Cancer Clin Oncol 1985 (Hodgkin Disease) : Peripheral blood lymphocytes ( PBL ) of patients with Hodgkin 's disease were studied for their capacity to produce interleukin 2 upon in vitro phytohemaglutinin stimulation in the presence or absence of either interleukin 1 or indomethacin ( 2 micrograms/ml ) ; eight patients were studied at the discovery of their disease before receiving any therapy ( onset HD ; OHD )
Solbach et al., Blood 1984 (Sezary Syndrome) : In this article we have studied the effects of the immunosuppressive drug cyclosporine A ( CsA ) on growth, interleukin-2 (IL-2) production, and the induction of IL-2 responsiveness of peripheral blood monocytes ( PBMs ) from five patients with Sézary 's syndrome in vitro, using the lectin phytohemagglutinin ( PHA ) and the phorbol ester phorbol myristate acetate ( PMA ) as stimuli
Knop et al., Hautarzt 1984 (Dermatitis, Atopic...) : The production of interleukin 2 is induced by interleukin 1, which can be also produced by keratinocytes ( epidermal T-cell activating factor, ETAF )
Bunjes et al., Eur J Immunol 1981 : The selective effects included a blockade of interleukin 2 release from activated T helper cells on the one hand and inhibition of interleukin 1 release from splenic adherent cells on the other
Hersey et al., J Immunol 1983 (Cell Transformation, Neoplastic...) : These supernatants did not inhibit interleukin 1 production, and also did not inhibit the mitogenic activity of performed IL 2 on IL 2-dependent target cells
Okada et al., Proc Natl Acad Sci U S A 1981 : In a clone ( 38-B ) that did not show any IL-2 activity in culture supernatants, the addition of macrophages induced IL-2 production in the presence of phytohemagglutinin, suggesting that interleukin-1 induced IL-2 production in T hybrid cells
He et al., Scand J Immunol 1995 : While IL-7 preferentially promoted the appearance of CD4 single positive and CD4+8+ double positive thymocytes, IL-2 primarily induced CD8 single positive thymocytes
Kees et al., J Immunol Methods 1994 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : A new human cell line for the molecular dissection of the requirement for interleukin-1 in the production of interleukin-2 by immature T cells
Xu et al., Kidney Int 1995 : Our investigation demonstrated that : ( a ) intragraft expression of IL-10 mRNA and IL-2 mRNA are significant correlates of acute rejection ; ( b ) IL-4, IL-7 , IFN-gamma and TGF-beta 1 mRNA expression do not correlate with acute rejection ; and ( c ) IL-10 does not prevent in vivo expression of IFN-gamma, IL-2 , IL-7, or TGF-beta 1
Fujihashi et al., Proc Natl Acad Sci U S A 1996 : Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor positive intraepithelial lymphocytes
Armant et al., Eur J Immunol 1996 : Functional CD40 ligand expression on T lymphocytes in the absence of T cell receptor engagement : involvement in interleukin-2 induced interleukin-12 and interferon-gamma production
Gringhuis et al., Blood 1997 (Leukemia-Lymphoma, Adult T-Cell) : Interleukin-7 upregulates the interleukin-2-gene expression in activated human T lymphocytes at the transcriptional level by enhancing the DNA binding activities of both nuclear factor of activated T cells and activator protein-1 ... In the present report, we studied the role of the stromal derived cytokine interleukin-7 (IL-7) in the IL-2-gene regulation in activated T lymphocytes ... The IL-2-gene transcription rate is increased 3.4-fold, indicating that the effect of IL-7 is in part mediated at the transcriptional level
Fukui et al., Immunol Lett 1997 : IL-7 induces proliferation, variable cytokine producing ability and IL-2 responsiveness in naive CD4+ T-cells from human cord blood