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GRAP2 — MMP2

Text-mined interactions from Literome

Ko et al., Mol Cancer Ther 2005 (Carcinoma...) : ERK inhibitor ( PD98059 ) and PKC inhibitors ( GF-109203X and H-7 ), but not p38 inhibitor ( SB203580 ) or c-jun-NH2-kinase inhibitor ( SP600125 ), significantly inhibited TPA induced MMP-2 protein expression, with reduced ERK phosphorylation and c-Jun protein expression
Park et al., Cancer Res 2006 (Glioblastoma...) : In addition, inhibitors of epidermal growth factor receptor ( EGFR ; AG490 and AG1478 ), Src ( PP2 ), and p38 ( SB203580 ), EGFR neutralizing antibody, and transfection of DN-Src and DN-p38 significantly blocked IR-induced Akt phosphorylation and MMP-2 secretion
Song et al., Cancer Res 2006 (Breast Neoplasms...) : Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells
Cheung et al., Cancer Res 2006 (Neoplasm Invasiveness...) : In addition, we showed that the c-Jun NH ( 2 ) -terminal kinase, but not extracellular signal regulated kinase 1/2 or p38 mitogen activated protein kinase, signaling pathway was critical for GnRH mediated up-regulation of MMP , cell invasion, and motility
Sanka et al., Invest Ophthalmol Vis Sci 2007 : Primary human TM ( HTM ) cells treated with different actin cytoskeleton interfering agents, including cytochalasin D, latrunculin A, ethacrynic acid ( ECA ), a Rho kinase inhibitor ( Y-27632 ), and H-7 ( serine/threonine kinase inhibitor ), were examined for changes in actin cytoskeletal organization by phalloidin staining, MMP-2 activation by gelatin zymography, expression of MT1-MMP by quantitative real-time PCR analysis, levels of tissue inhibitor of metalloproteinases ( TIMP-1 and TIMP-2 ), and activation of p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular signal regulated protein kinase ( ERK ) by immunoblotting ... Primary human TM ( HTM ) cells treated with different actin cytoskeleton interfering agents, including cytochalasin D, latrunculin A, ethacrynic acid ( ECA ), a Rho kinase inhibitor ( Y-27632 ), and H-7 ( serine/threonine kinase inhibitor ), were examined for changes in actin cytoskeletal organization by phalloidin staining, MMP-2 activation by gelatin zymography, expression of MT1-MMP by quantitative real-time PCR analysis, levels of tissue inhibitor of metalloproteinases ( TIMP-1 and TIMP-2 ), and activation of p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular signal regulated protein kinase ( ERK ) by immunoblotting
Chang et al., Evidence-based complementary and alternative medicine : eCAM 2011 : Schwann Cell Migration Induced by Earthworm Extract via Activation of PAs and MMP2/9 Mediated through ERK1/2 and p38
Hsu et al., J Cell Physiol 2012 (Colonic Neoplasms) : After administration of inhibitors including QNZ ( NF?B inhibitor ), LY294002 ( Akt activation inhibitor ), U0126 ( ERK1/2 inhibitor ), SB203580 ( p38 MAPK inhibitor ) or SP600125 ( JNK1/2 inhibitor ), E ( 2 ) -downregulated cell migration and expression of MMP-2 and MMP-9 in LoVo cells is markedly inhibited only by p38 MAPK inhibitors, SB203580
Yen et al., TheScientificWorldJournal 2013 (Gingival Neoplasms...) : After CTXIII treatment, the MMP-2 and MMP-9 protein expressions were downregulated, and the phosphorylation of JNK and p38-MAPK was increased independent of ERK phosphorylation
Pan et al., Mol Biol Rep 2013 (MAP Kinase Signaling System...) : Furthermore, SDF-1a induced p38 phosphorylation and p38 inhibition reduced both the level of SDF-1a stimulated MMP-2 expression and PANC-1 cell invasion