Gene interactions and pathways from curated databases and text-mining

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HDAC3 — STAT1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: STAT1 → HDAC3 (increases, HDAC3 Activity) Klampfer et al., J Biol Chem 2004*
    Evidence: silencing of HDAC1, HDAC2, and HDAC3 through RNA interference markedly decreased IFNgamma-driven gene activation and that overexpression of HDAC1, HDAC2, and HDAC3 enhanced STAT1-dependent transcriptional activity.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *