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CDH5 — PAK1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Birukova et al., Am J Physiol Lung Cell Mol Physiol 2008
:
Molecular inhibition of paxillin also attenuated OxPAPC induced enhancement of adherens junctions critical for the EC barrier-protective response, accumulation of
vascular endothelial cadherin in the membrane fractions, and decreased
activation of Rac and its effector p21 activated kinase (
PAK1 )
Yan et al., Stroke 2013
(Subarachnoid Hemorrhage) :
Downstream to PAR-1, c-Src dependent activation of
p21 activated kinase-1 led to an increased serine/threonine phosphorylation of vascular
endothelial-cadherin ; immunoprecipitation results revealed an enhanced binding of phosphorylated vascular endothelial-cadherin with endocytosis orchestrator ß-arrestin-2 ... Downstream to PAR-1, c-Src dependent activation of
p21 activated kinase-1 led to an increased serine/threonine phosphorylation of
vascular endothelial-cadherin ; immunoprecipitation results revealed an enhanced binding of phosphorylated vascular endothelial-cadherin with endocytosis orchestrator ß-arrestin-2