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BMP7 — DKK1
Text-mined interactions from Literome
Hufton et al., BMC developmental biology 2006
:
To this end, we ectopically overexpress Noggin and
Dkk-1 ,
inhibitors of the
BMP and Wnt pathways, respectively, within ventral tissues
Dai et al., Cancer Res 2008
(Neoplasm Metastasis...) :
DKK-1 blocked Wnt activation of the
BMP promoters ... The addition of
DKK-1 and Noggin, a
BMP inhibitor , to CM diminished PCa CM-induced osteoblast differentiation in a synergistic fashion
Miura et al., Dev Biol 2010
:
These data indicate that
BMP signaling in the epiblast
induces Wnt3 and Wnt3a expression to maintain WNT signaling in the VE, resulting in downregulation of
Dkk1 to establish the anterior expression domain ... Thus, our results suggest that
BMP signaling
regulates the expression patterns of
Dkk1 for anterior migration of the AVE