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IFI44 — PI3

Text-mined interactions from Literome

Mocanu et al., J Mol Cell Cardiol 2002 : Selective PI3 kinase inhibitors, wortmannin ( W, 100 n M ) and LY294002 ( LY, 15 microM ) and the p42/p44 inhibitor , PD 98059 ( PD, 10 and 50 microM ), were individually infused during the preconditioning protocol
Majka et al., Exp Hematol 2002 (MAP Kinase Signaling System) : Further, in an attempt to correlate the influence of these factors on cell proliferation and survival with activation of signal transduction pathways, we evaluated their effect on the phosphorylation of MAPK p42/44 and activation of PI-3K-AKT and JAK-STAT proteins in these various cell types
Offertáler et al., Mol Pharmacol 2003 : In human umbilical vein endothelial cells, abn-cbd induces phosphorylation of p42/44 mitogen activated protein kinase and protein kinase B/Akt, which is inhibited by O-1918, by pertussis toxin or by phosphatidylinositol 3 (PI3) kinase inhibitors
Nakatani et al., Biochem Biophys Res Commun 2007 : Treatment of 3Y1 cells with AVP resulted in transient activation of p44/42 mitogen activated protein kinase ( MAPK ) and cPLA(2)alpha, and phosphatidylinositol 3-kinase (PI3K) inhibitor blocked not only AVP induced PGE ( 2 ) synthesis but also MAPK activation, suggesting that PI3K is involved in the AVP induced MAPK and cPLA(2)alpha activation, which initiates the production of PGE ( 2 )
Xu et al., Int J Mol Med 2013 : In another set of cultures, the cells were co-incubated with RTB and the tyrosine kinase inhibitor, genistein, the phosphatidylinositol 3-kinase (PI3K) inhibitor, LY294002, the p42/44 inhibitor , PD98059, the p38 inhibitor, SB203580, the JNK inhibitor, SP600125, the protein kinase C ( PKC ) inhibitor, staurosporine, the JAK2 inhibitor, tyrphostin ( AG490 ), or the NOS inhibitor, L-NMMA