Gene interactions and pathways from curated databases and text-mining

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CRH — SST

Text-mined interactions from Literome

Riedel et al., Z Rheumatol 1998 : CRH , on the one hand, activates the pituitary-adrenal axis, but also stimulates at the hypothalamic level somatostatin secretion which, in turn, causes inhibition of GH and TSH at the pituitary level
Neeck et al., Scand J Rheumatol Suppl 2000 (Fibromyalgia...) : In addition to the stimulation of pituitary ACTH secretion, CRH activates somatostatin on the hypothalamic level, which in turn inhibits the release of GH and TSH on the hypophyseal level
Bueno et al., Gastroenterology 1986 : Effects of corticotropin releasing factor on plasma motilin and somatostatin levels and gastrointestinal motility in dogs
Low et al., J Biol Chem 1986 : Growth hormone releasing hormone, thyrotropin releasing hormone, corticotropin releasing factor , and dopamine did not affect somatostatin secretion