Gene interactions and pathways from curated databases and text-mining

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AHSA1 — PPARG

Text-mined interactions from Literome

Puigserver et al., Mol Cell 2001 (Cachexia) : Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1
Schild et al., Placenta 2006 : Here we tested the hypothesis that p38 plays an important role in the regulation of PPARgamma in primary human trophoblasts ... Our data support an effect of p38 on PPARgamma protein stability because p38 inhibition led to reduced expression of PPARgamma protein without a significant effect on PPARgamma mRNA, and this reduction was blocked by the protease inhibitor MG-132 ... Together, these data indicate that p38 regulates PPARgamma expression and activity in term human trophoblasts
Stanton et al., J Cell Mol Med 2010 : PPARgamma2 expression in growth plate chondrocytes is regulated by p38 and GSK-3 ... PPARgamma expression is suppressed by p38 activity, but requires GSK-3 activity