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CD44 — IL4
Text-mined interactions from Literome
Kryworuchko et al., Cell Immunol 1999
(Burkitt Lymphoma) :
Regulation of
CD44-hyaluronan interactions in Burkitt 's lymphoma and Epstein-Barr virus transformed lymphoblastoid B cells by PMA and
interleukin-4
Gee et al., Cell Immunol 2001
(Burkitt Lymphoma) :
Differential
effect of
IL-4 and IL-13 on
CD44 expression in the Burkitt 's lymphoma B cell line BL30/B95-8 and in Epstein-Barr virus ( EBV ) transformed human B cells : loss of IL-13 receptors on Burkitt 's lymphoma B cells ... In this study, we demonstrate that
IL-4 and IL-13 exhibited differential
effects on CD23 and
CD44 expression and binding to hyaluronan in BL30/B95-8, a Burkitt 's lymphoma ( BL ), and MK3.31, an Epstein-Barr virus transformed normal human B cell line ( B-LCL )
Macdonald et al., Eur J Gastroenterol Hepatol 2003
(Colitis, Ulcerative...) :
IL-4 and IL-13 are potent
inducers of CD44v6 and
CD44v3 expression on colon epithelial cells ... We have identified increased adhesion between lymphocytes and colon epithelial cells caused by
IL-4 induced
CD44v6 expression
Ibrahim et al., Int J Gynecol Cancer 2006
(Adenocarcinoma...) :
The
effects of interleukin (IL)-1alpha, IL-1beta,
IL-4 , IL-13, transforming growth factor (TGF)-beta1, estrogen, and progestogen on
CD44v5 expression were examined in cultures of three human cervical adenocarcinoma cell lines ( HeLa, HeLa229, and HS588T )
Jin et al., J Leukoc Biol 2006
:
After activation of B cells with CD40 and LPS,
IL-4 and IL-21 distinctively
regulated the expression of CD23,
CD44 , and CD138, and they cooperatively promoted IgG1 class switching and synthesis
Natesan et al., J Immunol 1996
:
CD44low , naive CD4+ T lymphocytes, could only be
induced to produce
IL-4 by repeated stimulation with B7 transfectants
Trejdosiewicz et al., Cytokine 1998
:
All cell lines expressed IL-4 receptors, but
IL-4 and IL-13
induced upregulation of
CD44 only in the colonic cell lines ...
CD44 upregulation in mitogen activated PBL was not
increased by
IL-4 and IL-13 and was not inhibited by neutralizing antibodies