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CDC25A — E2F1

Pathways - manually collected, often from reviews:

• NCI Pathway Database E2F transcription factor network: E2F1/DP complex (E2F1-TFDP2_TFDP1) → CDC25A (CDC25A) (transcription, activates) Chen et al., Mol Cell Biol 1999, Vigo et al., Mol Cell Biol 1999
  Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Vigo et al., Mol Cell Biol 1999 : Data showing that CDC25A is an essential target for E2F-1 , since its activity is required for efficient induction of S phase by E2F-1, are provided
Santoni-Rugiu et al., Mol Cell Biol 2000 : Finally, proper transcription of cyclin E and Cdc25A at the G ( 1 ) /S transition requires both Myc and E2F activities, and subthreshold levels of ectopic cyclin E and Cdc25A synergistically restore DNA synthesis in cells with silenced Myc and E2F activities