Gene interactions and pathways from curated databases and text-mining

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MMP3 — PDLIM7

Text-mined interactions from Literome

Boya et al., J Exp Med 2003 : LMP triggers mitochondrial membrane permeabilization ( MMP ) , as detected by the release of cytochrome c ... Bax-/- Bak-/- double knockout cells fail to undergo MMP and cell death in response to CPX- or NFX induced LMP
Kondo et al., Int J Cancer 2005 (Carcinoma, Squamous Cell...) : LMP1 transfected cells with 2G/2G genotype expressed MMP1, which was abolished by activator protein-1 (AP1) dominant negative ( DN ) and Ets-DN. LMP1 also induced active MMP3, which can cleave latent MMP1, and AP1-DN and Ets-DN suppressed the MMP3 expression ... These results suggest that LMP1 induced MMP1 and MMP3 are closely linked and show that LMP1 activates MMP1 via an Ets binding site formed by 2G, which is a candidate marker for both risk and prognosis of NPC
Lee et al., Biomed Pharmacother 2007 (Carcinoma...) : To investigate the role of LMP1 in MMP expression in NPC, we cloned the LMP1 gene from NPC samples and transiently expressed it in MRC5 cells ( human lung fibroblasts )