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MMP3 — PDLIM7
Text-mined interactions from Literome
Boya et al., J Exp Med 2003
:
LMP triggers mitochondrial
membrane permeabilization ( MMP ) , as detected by the release of cytochrome c ... Bax-/- Bak-/- double knockout cells fail to undergo
MMP and cell death in
response to CPX- or NFX induced
LMP
Kondo et al., Int J Cancer 2005
(Carcinoma, Squamous Cell...) :
LMP1 transfected cells with 2G/2G genotype expressed MMP1, which was abolished by activator protein-1 (AP1) dominant negative ( DN ) and Ets-DN.
LMP1 also induced active MMP3, which can cleave latent MMP1, and AP1-DN and Ets-DN
suppressed the
MMP3 expression ... These results suggest that
LMP1 induced MMP1 and
MMP3 are closely linked and show that LMP1 activates MMP1 via an Ets binding site formed by 2G, which is a candidate marker for both risk and prognosis of NPC
Lee et al., Biomed Pharmacother 2007
(Carcinoma...) :
To investigate the
role of
LMP1 in
MMP expression in NPC, we cloned the LMP1 gene from NPC samples and transiently expressed it in MRC5 cells ( human lung fibroblasts )