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CD40 — TRAF7
Text-mined interactions from Literome
Pullen et al., J Biol Chem 1999
:
These studies suggest a
role in
CD40 signaling for competitive
TRAF binding and imply that CD40 responses reflect an integration of signals from individual TRAFs
Leo et al., J Biol Chem 1999
:
In contrast,
TRAF6 ( DeltaN ) did not
impair JNK activation by
CD40 ( Delta32 )
Webster-Cyriaque et al., J Virol 2000
(AIDS-Related Opportunistic Infections...) :
Effects
induced by activated
TRAF signaling that were detected in HLP included activation of NF-kappaB and c-Jun terminal kinase 1 (JNK1) and upregulated expression of epidermal growth factor receptor (EGFR),
CD40 , A20, and TRAFs
Hostager et al., J Immunol 2002
:
Furthermore, although both CD40 and CD120b can bind TRAF2,
TRAF2 dependent
CD40 signals can not substitute for TRAF2 dependent CD120b signals in the activation of IgM secretion
Li et al., American journal of physiology. Renal physiology 2002
:
CD40 ligation
stimulates MCP-1 and IL-8 production,
TRAF6 recruitment, and MAPK activation in proximal tubule cells
Chan et al., Biochem Biophys Res Commun 2005
:
TRAF dependent association of protein kinase Tpl2/COT1 ( MAP3K8 ) with
CD40
Graham et al., J Immunol 2009
:
LMP1 does n't
induce TRAF degradation, and employs TRAF3 as a positive mediator of cell signaling, whereas
CD40 signals are inhibited by TRAF3