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IDO1 — NFKB1

Text-mined interactions from Literome

Muller et al., Nat Med 2005 (Cell Transformation, Neoplastic...) : Mouse knockout studies indicate that Bin1 loss elevates the STAT1- and NF-kappaB dependent expression of IDO , driving escape of oncogenically transformed cells from T cell dependent antitumor immunity
Fujigaki et al., J Biochem 2006 : Further, the LPS induced IDO activity was inhibited by both p38 mitogen activated protein kinase ( MAPK ) and nuclear factor-kappaB (NF-kappaB) inhibitors
Grohmann et al., Nat Med 2007 (Disease Models, Animal...) : Here we show that reverse signaling through GITRL after engagement by soluble GITR initiates the immunoregulatory pathway of tryptophan catabolism in mouse plasmacytoid dendritic cells, by means of noncanonical NF-kappaB dependent induction of indoleamine 2,3-dioxygenase (IDO)
Tas et al., Blood 2007 (Inflammation) : Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation ... By selective blocking of either the canonical NF-kappaB pathway using the NEMO binding domain peptide or the noncanonical NF-kappaB pathway by small interfering RNA, we demonstrate that IDO expression requires noncanonical NF-kappaB signaling
Suh et al., J Virol 2007 (Cytomegalovirus Infections...) : PIC induction of IDO was mediated in part by IFN-beta but not IFN-gamma, and both NF-kappaB and interferon regulatory factor 3 (IRF3) were required
Puccetti et al., Nat Rev Immunol 2007 : IDO and regulatory T cells : a role for reverse signalling and non-canonical NF-kappaB activation
Ogasawara et al., J Cell Biochem 2009 : Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species ... Hb-induced IDO expression was inhibited by inhibitors of PI3-kinase (PI3K), PKC and nuclear factor (NF)-kappaB ... These results suggest that the activation of NF-kappaB through the PI3K-PKC-ROS and PI3K-Akt pathways is required for the Hb-induced IDO expression in BMDCs