Gene interactions and pathways from curated databases and text-mining

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GIT1 — PLCG2

Text-mined interactions from Literome

Haendeler et al., J Biol Chem 2003 : GIT1 mediates Src dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor
Pang et al., Circulation 2009 : Because activation of phospholipase-Cgamma ( PLCgamma ) and extracellular signal regulated kinases 1/2 ( ERK1/2 ) by angiotensin II requires GIT1 , we hypothesized that GIT1 mediates VEGF dependent pulmonary angiogenesis by modulating PLCgamma and ERK1/2 activity in endothelial cells