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NOS1 — NPPA

Text-mined interactions from Literome

González Bosc et al., Peptides 1999 : Our results show that ANP enhances NOS-NADPH-d activity, suggesting that ANP stimulates NO synthase in enterocytes by L-arginine-NO pathway
Ventura et al., Braz J Med Biol Res 2002 : The central inhibition of NOS by L-NAME caused a decrease in plasma AVP and no change in plasma OT or ANP levels after BVE
Madhani et al., Br J Pharmacol 2003 : Both ANP and CNP were more potent in aortae from eNOS KO mice compared to WT. ( 3 ) The potency of ANP and CNP in aortae from WT animals was increased in the presence of the NOS inhibitor, N ( G ) -nitro-L-arginine ( 3 x 10 ( -4 ) M ) and the soluble guanylate cyclase inhibitor 1H- [ 1,2,4 ] oxadiazolol [ 4,3,a ] quinoxalin-1-one ( 5 x 10 ( -6 ) M )
de los Angeles Costa et al., Regul Pept 2004 : The aim was to investigate ANP effects on renal and cardiac NO-synthase (NOS) activity ... NOS activity was increased by in vitro ANP addition and, in vivo, ANP infusion in all the studied tissues
Costa et al., Regul Pept 2006 : The aim was to investigate the natriuretic receptor type and the signaling cascade involved in NOS activation induced by ANP ... ANP and cANP ( 4-23 ), a selective NPR-C ligand, increased NOS activity in all tissues ... Gi inhibition with pertussis toxin abolished NOS activity stimulated by ANP and cANP in atria but only partially inhibited the increased NOS activity induced by ANP and cANP in kidney, aorta and ventricle ... Our results show that NPR-C receptor would mediate the activation of NOS by ANP in atria
Borán et al., Glia 2008 : However, ANP does not induce NO synthase Type 2 (NOS-2) or tumor necrosis factor-alpha expression and is able to decrease lipopolysaccharide (LPS) elicited induction of these inflammatory genes
Elesgaray et al., Regul Pept 2008 : Atrial natriuretic peptide (ANP) induces activation of nitric oxide-synthase (NOS) ... NOS activation induced by ANP would be mediated by endothelial NOS (eNOS) since neuronal or inducible NOS inhibition did not alter ANP effect ... 8-Br-cGMP partially mimicked the effect of ANP on NOS in all tissues ... NOS stimulation by ANP in atria disappeared when G protein was inhibited, but this effect was partial in the other tissues ... Inhibition of the PLC, PKC or PI3 kinase/Akt pathway failed to alter NOS activation induced by ANP
Costa et al., Am J Physiol Heart Circ Physiol 2010 (Disease Models, Animal...) : In vitro, heart and aortic NOS activity induced by ANP was determined in the presence of iNOS and nNOS inhibitors, natriuretic peptide receptor (NPR)-A/B blocker, G ( i ) protein, and calmodulin inhibitors ... ANP increased NOS activity, but the activation was lower in SHRs than in WKY rats ... ANP had no effect on NOS isoform expression ... NOS activity induced by ANP was not modified by iNOS and nNOS inhibitors ... Cardiovascular NOS response to ANP was reduced by G ( i ) protein and calmodulin inhibitors in both groups ... The NOS response to ANP was impaired in heart and aorta of SHRs
Elesgaray et al., American journal of physiology. Renal physiology 2012 : We investigated the effects of ANP on the NO system in SHR, studying the changes in renal nitric oxide synthase (NOS) activity and expression in response to peptide infusion, the signaling pathways implicated in the signaling cascade that activates NOS, and identifying the natriuretic peptide receptors ( NPR ), guanylyl cyclase receptors ( NPR-A and NPR-B ) and/or NPR-C, and NOS isoforms involved ... In vitro, ANP induced renal NOS activity was determined in the presence of iNOS and nNOS inhibitors, NPR-A/B blockers, guanine nucleotide-regulatory ( G ( i ) ) protein, and calmodulin inhibitors ... ANP increased NOS activity, but activation was lower in SHR than in WKY ... ANP induced NOS activity was not modified by iNOS and nNOS inhibitors ... The renal NOS response to ANP was reduced by G ( i ) protein and calmodulin inhibitors ... The NOS response to ANP was diminished in kidneys of SHR