Gene interactions and pathways from curated databases and text-mining

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RPTOR — TNF

Text-mined interactions from Literome

Wang et al., Oncology 2007 (Disease Models, Animal...) : Either siRNA Raptor or siRNA Rictor suppressed TNF-alpha expression, but the latter suppressed the effects of GM3 on TNF-alpha expression and Akt phosphorylation at Ser ( 473 ), indicating the GM3 signal to be transduced via Rictor/mTOR and Akt ( Ser ( 473 ) ), leading to TNF-alpha stimulation
Zhang et al., Basic Res Cardiol 2012 (Calcium Signaling...) : The aim of this study was to investigate the role of Na/K-ATPase/mTOR signaling in myocardial TNF-a expression during endotoxemia