◀ Back to MSH4
MITF — MSH4
Text-mined interactions from Literome
Huber et al., J Biol Chem 2003
(Neuroblastoma) :
Although
M-MITF promoter
activation by
MSH is known to occur through a conserved cAMP-response element ( CRE ), it remains unclear how this CRE exhibits such exquisitely tissue restricted responsiveness
Kim et al., Biol Pharm Bull 2007
(Melanoma, Experimental) :
Moreover, alpha-melanocyte stimulating hormone ( alpha-MSH ) is known to increase melanin biosynthesis by increasing tyrosinase production, and here, we found that
alpha-MSH induced
Mitf and tyrosinase increases were inhibited in B16 melanoma cells treated with KHG22394
Yang et al., Mol Cell 2008
:
The activation of
p53-POMC/MSH-MC1R signaling is
required for the UV-induced melanogenic response because PAX3 functions in synergy with SOX10 in a cAMP-response element ( CRE ) -dependent manner to regulate the transcription of
Mitf
Shoag et al., Mol Cell 2013
(Genetic Predisposition to Disease...) :
Inhibition of PGC-1a and PGC-1ß blocks the
a-MSH mediated
induction of
MITF and melanogenic genes