Kim et al., Biochem Biophys Res Commun 2005
(Body Weight) :
In situ hybridization analysis revealed that the expression levels of AGRP and NPY in the hypothalamus were significantly and rapidly diminished while POMC expression was strongly induced by [ Gln ( 6 ) ] alpha-MSH-ND Lee et al., Peptides 2008
:
We now demonstrate that central activation of MC3-R with ICV infusion of the specific MC3-R agonist, [ D-Trp ( 8 ) ] -gamma-MSH , transiently suppresses hypothalamic Pomc expression and stimulates food intake in rats
Nan et al., Br J Dermatol 2008
(Carcinoma, Basal Cell...) :
Induction of POMC/alpha-melanocyte stimulating hormone ( alpha-MSH ) activates the melanocortin 1 receptor (MC1R), resulting in skin pigmentation