Gene interactions and pathways from curated databases and text-mining

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CD4 — CISH

Text-mined interactions from Literome

Tormo et al., Cytokine 2012 : CD4 T cell stimulation with IL-6 induces the synthesis of CIS , which is encoded by a gene known to be regulated by STAT5
Carow et al., PLoS Pathog 2013 : Instead, SOCS3 expression in infected macrophages and DCs prevented the IL-6 mediated inhibition of TNF and IL-12 secretion and contributed to a timely CD4+ cell dependent IFN-? expression in vivo