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PTGS2 — WDR61

Text-mined interactions from Literome

Alvi et al., Immunology 1999 : The antibody to IL-1beta did not affect CRH stimulated or PAF stimulated PGE2 production or COX-2 expression
Munir et al., J Reprod Fertil 1999 (Adenocarcinoma...) : PAF induced COX-2 expression was insensitive to PD098059 but sensitive to wortmannin, whereas hCG induced COX-2 expression was sensitive to PD098059 and H-89 but insensitive to wortmannin
Walterscheid et al., J Exp Med 2002 : Both UV and PAF activated cyclooxygenase (COX)-2 and IL-10 reporter gene construct transcription
Wang et al., Scand J Gastroenterol 2002 (Carcinoma, Squamous Cell...) : 59 ESCC samples were used to assess COX-2 expression in the tumor cells and four ESCC cell lines to investigate the effects of phorbol myristate acetate ( PMA ), platelet activating factor (PAF) , n-sodium butyrate ( n-BT ) and interleukin-6 (IL-6) on the expression of COX-2
Kolko et al., Neurosci Lett 2003 : We conclude that sPLA ( 2 ) -OS2 activates a neuronal signaling cascade that includes activation of cPLA(2), arachidonic acid release, PAF production, and induction of COX-2
Fang et al., Eur J Surg Oncol 2003 (Carcinoma, Non-Small-Cell Lung...) : The expression of COX-2 in NSCLC cells is high and was up-regulated by PMA, n-BT and PAF
Bouayad et al., Am J Physiol Regul Integr Comp Physiol 2004 : Because platelet activating factor (PAF) could regulate COX-2 expression, the former was measured and found to be more abundant in the DA of the NB than of fetus
Gray et al., Mol Pharmacol 2004 : We also observed that tumor necrosis factor (TNF)-alpha, platelet activating factor (PAF) , and lipopolysaccharide (LPS) induced COX-2 and increased MUC5AC production that was blocked by celecoxib, suggesting a common signaling pathway of inflammatory mediator induced MUC5AC production in NHTBE cells
Vardar et al., J Periodontol 2005 (Disease Models, Animal...) : The present study was planned to evaluate the individual and combined effects of selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, and omega-3 fatty acid on the gingival tissue levels of prostaglandin E2 ( PGE2 ), prostaglandin F2alpha ( PGF2alpha ), leukotriene B4 (LTB4), and platelet activating factor (PAF) in endotoxin induced periodontitis in rats
Boetkjaer et al., Neurosci Lett 2007 (Encephalitis) : The data indicate that these three biochemically unrelated classes of inflammatory repressors act synergistically in modulating PAF induced up-regulation of COX-2 , TNFalpha, and PGE ( 2 ) by quenching oxidative stress or inflammatory signaling, resulting in increased HN cell survival
Thivierge et al., J Immunol 1995 : These results suggest that COX-2 expression can be regulated at the transcriptional level by PAF , in synergy with bacterial products ... PAF dependent up-regulation of COX-2 expression may constitute a novel element in the interrelationship between PAF and prostanoids in the context of allergic, inflammatory, and immune processes
Bazan et al., Invest Ophthalmol Vis Sci 1997 : In a Ca ( 2+ ) -free medium, there was a 50 % inhibition of COX-2 gene induction by PAF
Bazan et al., Prog Brain Res 1998 (Neurodegenerative Diseases...) : PAF is a transcriptional activator of the COX-2 gene