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RB1 — SMARCA4

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of NR3C1-SMARCA4 → RB1 (increases) Marshall et al., J Biol Chem 2003*
  Evidence: In contrast, RB enhances association of the glucocorticoid receptor (GR) with either BRG1 or hBRM, thus resulting in increased GR activity (51-53). The association between BRG1 or hBRM and GR is known to be direct, and recruitment of SWI/SNF complexes to GR may actually stimulate displacement of GR from chromatin, allowing GR to return to the remodeled chromatin with additional transcription factors (30).
• OpenBEL Selventa BEL large corpus: Complex of NR3C1-SMARCA4 → RB1 (increases) Marshall et al., J Biol Chem 2003*
  Evidence: RB enhances association of the GR with either BRG1 or BRM, resulting in increased GR activity
• OpenBEL Selventa BEL large corpus: Complex of RB1-SMARCA4 → RB1 (directlyIncreases)
  Evidence: Rb phosphorylation changes Rb pocket conformation Change in Rb pocket conformation allow Rb binding to BRG1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: SMARCA4 — RB1 (direct interaction, two hybrid) Dunaief et al., Curr Eye Res 2002*
• IRef Biogrid Interaction: SMARCA4 — RB1 (physical association, affinity chromatography technology) Dunaief et al., Cell 1994*
• IRef Biogrid Interaction: SMARCA4 — RB1 (colocalization, biochemical) Reyes et al., J Cell Biol 1997*
• IRef Biogrid Interaction: SMARCA4 — RB1 (physical association, affinity chromatography technology) Qiu et al., Neuron 2008*
• IRef Biogrid Interaction: SMARCA4 — RB1 (physical association, affinity chromatography technology) Dasgupta et al., Mol Cell Biol 2004*
• IRef Biogrid Interaction: SMARCA4 — RB1 (physical association, affinity chromatography technology) Zhang et al., Cell 2000
• IRef Biogrid Interaction: SMARCA4 — RB1 (physical association, affinity chromatography technology) Napolitano et al., J Cell Sci 2007*
• MIPS CORUM RB1-HDAC1-BRG1 complex: RB1-HDAC1-BRG1 complex complex (HDAC1-RB1-SMARCA4) Zhang et al., Cell 2000
• IRef Corum Interaction: Complex of SMARCA4-RB1-HDAC1 (association, anti tag coimmunoprecipitation) Zhang et al., Cell 2000
• IRef Hprd Interaction: SMARCA4 — RB1 (two hybrid) Dunaief et al., Cell 1994*
• IRef Hprd Interaction: SMARCA4 — RB1 (in vivo) Dunaief et al., Cell 1994*
• IRef Ophid Interaction: SMARCA4 — RB1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005