◀ Back to CXCR4
CXCR4 — TNFSF10
Text-mined interactions from Literome
Lum et al., AIDS 2005
(HIV Infections) :
The increase in
TRAIL death receptor expression and acquisition of TRAIL sensitivity
requires the chemokine coreceptor
CXCR4 but not CCR5 or the CD4 receptor
Lum et al., J Immunol 2005
:
Thus, SDF-1 ligation of
CXCR4 causes the parallel processes of chemotaxis and
enhanced TRAIL and
TRAIL death receptor expression, resulting in apoptosis of senescent neutrophils upon their return to the bone marrow
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2010
(Multiple Myeloma) :
Moreover,
TRAIL up-regulated the expression level of adherent molecule
CXCR4 in RPMI8226 cells significantly ... It is concluded that
TRAIL up-regulated the expression level of adherent molecule
CXCR4 in RPMI8226 cells significantly, and induced the apoptosis of RPMI8226 cells
Wang et al., FEBS J 2013
(Breast Neoplasms) :
These results were confirmed in a human breast cancer xenograft mouse model, suggesting that
TRAIL significantly enhanced miR-146a expression and
suppressed CXCR4 expression, indicating that TRAIL induced miR-146a up-regulation is negatively associated with CXCR4 expression