Gene interactions and pathways from curated databases and text-mining

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CXCL8 — MAPK3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CXCL8 → MAPK3 (increases, CXCL8 Activity) Oh et al., J Immunol 2001*
    Evidence: SDF-1alpha-induced chemokine expression was abrogated upon inclusion of U0126, a pharmacological inhibitor of ERK1/2, indicating that the ERK signaling cascade is involved in this response.