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HMOX1 — IL19
Text-mined interactions from Literome
Gabunia et al., J Biol Chem 2012
(Vasculitis) :
Interleukin-19 (IL-19) induces
heme oxygenase-1 (HO-1) expression and decreases reactive oxygen species in human vascular smooth muscle cells ...
IL-19 activates STAT3 in VSMC, and IL-19 induced
HO-1 expression is significantly
reduced by transfection of VSMC with STAT3 siRNA or mutation of the consensus STAT binding site in the HO-1 promoter
Lee et al., J Agric Food Chem 2013
(Diabetes Mellitus, Type 2) :
It was found that monascin promoted
heme oxygenase-1 (HO-1) expression
mediated by Nrf2. Suppressions of AGEs, tumor necrosis factor-a (TNF-a), and
interleukin-1ß ( IL-ß ) in serum of MG-induced rats were attenuated in the monascin administration group treated with retinoic acid ( RA )
Collino et al., Dis Model Mech 2013
(Disease Models, Animal...) :
Besides, chronic
HO-1 activation
suppressed the elevated levels of myeloperoxidase (MPO) activity,
interleukin 1ß (IL-1ß) production and tumor necrosis factor-a (TNFa) production that were evoked by the ischemic injury, and increased the plasma level of the anti-inflammatory cytokine IL-10
Das et al., J Antimicrob Chemother 2013
(Leishmaniasis, Visceral) :
Furthermore,
HO-1 blockade by miltefosine led to suppression of interleukin-10 and transforming growth factor-ß, but
enhanced interleukin-12 and tumour necrosis factor-a production, in VL patients