Gene interactions and pathways from curated databases and text-mining

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CDK9 — SP1

Pathways - manually collected, often from reviews:

  • FastForward regulation: SP1 → CDK9 (transcriptional regulation, unknown)
    Evidence: DNABINDING

Text-mined interactions from Literome

Lu et al., Mol Endocrinol 2000 (Adenocarcinoma...) : Androgen induction of cyclin dependent kinase inhibitor p21 gene : role of androgen receptor and transcription factor Sp1 complex
PeƱuelas et al., Eur J Biochem 2003 : The expression of the transcription factor Sp1 , a retinoblastoma interacting protein, was also enhanced by all the cyclin dependent kinase inhibitors tested
Chew et al., J Biol Chem 2012 : Sulforaphane induction of p21 ( Cip1 ) cyclin dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53 dependent