Gene interactions and pathways from curated databases and text-mining

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EPHB2 — PDCD4

Text-mined interactions from Literome

Pleschka et al., Biol Chem 2008 (RNA Virus Infections) : Raf/MEK/ERK signaling leads to stimulus-specific changes in gene expression, alterations in cell metabolism or induction of programmed cell death ( apoptosis ), and thus controls cell differentiation and proliferation
Shen et al., PloS one 2013 (Cell Transformation, Neoplastic) : Down-regulation of miR-21 and up-regulations of Pdcd44 or Spry1 blocked the arsenite induced activations of JNK/c-Jun or ERK/NF-?B, indicating that knockdown of miR-21 inhibits feedback of ERK activation and JNK activation via increases of Pdcd4 and Spry1 protein levels, respectively