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EPHB2 — PDLIM7
Text-mined interactions from Literome
Chuang et al., Blood 2005
(Lymphohistiocytosis, Hemophagocytic) :
LMP1 mediated
SAP/ERK/IFN-gamma signals appear to act via the TNF receptor associated factor (TRAF)2,5/nuclear factor kappaB (NF-kappaB) pathway, since dominant negative TRAF2/5 and NF-kappaB inhibitor could rescue SAP expression and downregulate IFN-gamma
Kung et al., J Virol 2011
:
Epstein-Barr virus
LMP1 activates EGFR, STAT3, and
ERK through effects on PKCdelta ... Interestingly, inhibition of PKCd also inhibited constitutive phosphorylation of EGFR and
LMP1-CTAR1 induced phosphorylation of
ERK ... These findings indicate that LMP1 activates multiple distinct signaling pathways and suggest that PKCd functions as a master regulator of EGFR, STAT3, and
ERK activation by
LMP1-CTAR1
Liu et al., PloS one 2012
(Nasopharyngeal Neoplasms) :
ERK-specific small interfering RNA blunts
LMP1 induced kappa light chain gene expression ... PD98059 treatment also leads to a concentration dependent inhibition of LMP1 induced Ets-1 expression and phosphorylation, which corresponds with a dose dependent attenuation of
LMP1 induced
ERK phosphorylation and kappa light chain expression