Gene interactions and pathways from curated databases and text-mining

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RIPK1 — ZGLP1

Text-mined interactions from Literome

Skoglund et al., Diabetes 2000 (Insulinoma...) : Activation of RIP1 by GLP-1 was not affected by cotransfection with dominant negative Gs alpha, was not blocked by cAMP antagonist Rp-cAMPS, and was insensitive to PKA antagonist H-89
Chepurny et al., Cell Tissue Res 2002 (Diabetes Mellitus...) : The increase of basal RIP1-Luc activity is a consequence of autocrine stimulation by self secreted GLP-1 and is blocked by introduction of ( 1 ) an inactivating W39A mutation in the N-terminus ligand binding domain of GLP-1-R or ( 2 ) mutations in the third cytoplasmic loop that prevent G protein coupling