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RIPK1 — ZGLP1
Text-mined interactions from Literome
Skoglund et al., Diabetes 2000
(Insulinoma...) :
Activation of
RIP1 by
GLP-1 was not affected by cotransfection with dominant negative Gs alpha, was not blocked by cAMP antagonist Rp-cAMPS, and was insensitive to PKA antagonist H-89
Chepurny et al., Cell Tissue Res 2002
(Diabetes Mellitus...) :
The increase of basal
RIP1-Luc activity is a
consequence of autocrine stimulation by self secreted
GLP-1 and is blocked by introduction of ( 1 ) an inactivating W39A mutation in the N-terminus ligand binding domain of GLP-1-R or ( 2 ) mutations in the third cytoplasmic loop that prevent G protein coupling