Gene interactions and pathways from curated databases and text-mining

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GDNF — GYPB

Text-mined interactions from Literome

Oppenheim et al., J Neurosci 2000 : GDNF dependent MNs that are lost in GDNF-deficient animals express ret/GFRalpha1/islet-1, whereas many surviving GDNF independent MNs express ret/GFRalpha1/GFRalpha2 and islet-1/islet-2
Gould et al., J Neurosci 2008 : Finally, we demonstrated that the period during which spindle innervating MNs require GDNF for survival is restricted to early neonatal development, because mice in which the function of Ret or GFRalpha1 was inactivated after P5 failed to exhibit denervation of muscle spindles or MN loss