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EPHB1 — MAPK3
Pathways - manually collected, often from reviews:
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OpenBEL Selventa BEL large corpus:
MAPK3
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EPHB1
(increases, EPHB1 Activity, MAPK3 Activity)
Vindis et al., J Cell Biol 2003
Evidence: Here we demonstrate that activated EphB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation.
Text-mined interactions from Literome
Yosimichi et al., Eur J Biochem 2001
:
These inhibitors of MAPKK and
MAPK suppressed phosphorylation of
ets-like gene-1 (Elk-1) and nuclear activating transcription factor-2 ( Atf-2 ) induced by CTGF/Hcs24 in a dose dependent manner, respectively
Vindis et al., J Cell Biol 2003
:
Together these findings highlight a new aspect of
EphB1 signaling, whereby the concerted action of c-Src and p52Shc
activates MAPK/ERK and regulates events involved in cell motility
Geng et al., Neurochem Int 2013
:
Moreover,
EphB2 overexpression
prevented Aß1-42 oligomer induced downregulation of dephosphorylated p38
MAPK and phosphorylated CREB