Lee et al., Hepatology 2010
(Carcinoma, Hepatocellular...) :
Sprouty2 (Spry2) , a negative feedback regulator of the Ras/mitogen activated protein kinase ( MAPK ) pathway, is frequently down-regulated in human hepatocellular carcinoma ( HCC )
Li et al., J Biol Chem 2013
(Breast Neoplasms...) :
Forced expression of the miR-23a/24-2/27a cluster promoted mammary carcinoma cell migration, invasion, and hepatic metastasis, through targeting Sprouty2 (SPRY2) and consequent activation of p44/42 MAPK