Gene interactions and pathways from curated databases and text-mining

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HIPK4 — TP53

Text-mined interactions from Literome

Wang et al., BMC molecular biology 2001 : Instead, HIPK2 leads to a downregulation of p53 induced Mdm2 protein and this may lead to stabilization of p53
Guerra et al., PloS one 2012 : The HIPKs have been shown to be involved in growth regulation and apoptosis, with numerous studies highlighting HIPK regulation of the tumor suppressor p53