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AGTR1 — IL1A
Text-mined interactions from Literome
Wang et al., Apoptosis 2012
:
Overexpression of
AT1R and AT2R markedly
increased IL-1ß ( AT2R > AT1R ), iNOS ( AT2R > AT1R ) and eNOS expression
Lv et al., Braz J Med Biol Res 2012
:
In the PS group, TNF-a increased
at 1 , 3, and 5 weeks and
IL-1ß increased significantly after 1 and 3 weeks of stress, and then decreased to normal levels by 5 weeks
Kawakami et al., Arthritis 2012
:
The
effect of
IL-1 on
AT1R/AT2R expression in the chondrocytes was analyzed by quantitative PCR and flow cytometry ... Human articular chondrocytes, at least partially, express angiotensin II receptors, and
IL-1 stimulation
induced AT1R/AT2R mRNA expression significantly
Pignol et al., Prostaglandins 1987
:
PAF-acether
at 1pM increased
IL1 release by 120 +/- 39 % and synthesis by 87 +/- 27 % whereas at 0.1 microM a decrease of IL1 release of 52 +/- 9 % and synthesis of 46 +/- 6 % were observed
Oberyszyn et al., Mol Carcinog 1993
(Inflammation...) :
IL-1 alpha gene expression
increased in epidermal tissue isolated from SENCAR mice
at 1 , 3, 6, 10, 16, and 22 wk after a single treatment with 10 nmol 7,12-dimethylbenz [ a ] anthracene ( DMBA ) and subsequent twice-weekly application of 2 micrograms TPA
Sasamura et al., Hypertension 1997
:
We therefore examined the
effects of
interleukin-1 alpha ( 220 U/mL [ 10 ng/mL ] ), tumor necrosis factor-alpha ( 280 U/mL [ 100 ng/mL ] ), and interferon gamma ( 100 U/mL ) on
Ang II type 1 (AT1) receptors expressed in rat vascular smooth muscle cells ... Although the
upregulation of
AT1 by
interleukin-1 alpha was unaffected by pretreatment of cells with N-monomethyl-L-arginine or indomethacin, downregulation of AT1 by interleukin-1 alpha combined with tumor necrosis factor-alpha/interferon gamma was inhibited by N-monomethyl-L-arginine ( P < .01 ) ... These results demonstrate that
interleukin-1 alpha upregulates
AT1 receptors and enhances Ang II-stimulated hypertrophic responses