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ADAM10 — MYLIP
Text-mined interactions from Literome
Augustin et al., BMC medical genetics 2012
(Alzheimer Disease...) :
ADAM10 expression in the reporter assay was
reduced by
miR-1306 ( 28 % ), miR-103 ( 45 % ) and miR-107 ( 52 % )
Cheng et al., J Biol Chem 2013
(Alzheimer Disease) :
In this study, we demonstrated that overexpression of
miR-144 , which was previously reported to be increased in elderly primate brains and AD patients, significantly decreased activity of the luciferase reporter containing the ADAM10 3'-untranslated region ( 3'-UTR ) and
suppressed the
ADAM10 protein level, whereas the miR-144 inhibitor led to an increase of the luciferase activity ... In addition, we found that
miR-451 , a miRNA processed from a single gene locus with miR-144, is also
involved in the regulation of
ADAM10 expression