Gene interactions and pathways from curated databases and text-mining

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APOE — TLR4

Text-mined interactions from Literome

Ali et al., Circ Res 2005 (Inflammation) : This implies that apoE selectively regulates TLR4- and TLR3 mediated signaling of IL-12 production
Higashimori et al., Arterioscler Thromb Vasc Biol 2011 (Aortic Diseases...) : TLR4 deficiency reduced intimal lipid by ˜75 % in ApoE KO mice, despite unaltered total serum cholesterol and triglyceride levels, whereas TLR2 deficiency reduced it by ˜45 %