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CD44 — MIF

Text-mined interactions from Literome

Meyer-Siegler et al., J Immunol 2006 (Neoplasm Invasiveness...) : MIF interacts with its identified membrane receptor, CD74, in association with CD44 , resulting in ERK 1/2 activation
Berndt et al., Mol Cell Biochem 2008 : MIF signaling involves CD74/CD44 membrane receptor complexes, the chemokine receptors CXCR2 and 4 as well as uptake by non-receptor mediated endocytosis
Sanchez-Niño et al., Cytokine Growth Factor Rev 2013 (Inflammation...) : CD74, CD44 and CXCR4 are upregulated in renal cells in diseased kidneys and MIF activation of CD74 in kidney cells promotes an inflammatory response